Can i play mhfu in low end pc?

Can i play mhfu smoothly with intel celeron, 4Gb ram, and 1.80ghz?

You need to be more precise with your hardware, there are hundreds of Celeron CPUs.
Most important for getting smooth game play on Citra is having a CPU with a single thread performance of at least 1800 on this list https://www.cpubenchmark.net/singleThread.html

From the FAQ: