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That sounds like very outdated GPU drivers. Which GPU do you have?
I have Intel(R) HD Graphics 520 and I could open configuration in older versions of yuzu (I use yuzu 149 to edit the configuration)
Install the latest driver and it will work: https://downloadcenter.intel.com/download/29560/Intel-Graphics-BETA-Windows-10-DCH-Drivers?product=97502
Thank you for your help. I can now open the configuration.
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