Yuzu Compatibility for AMD 650

Is AMD 650 intel 620 enough to play on yuzu

In order for us to provide better support, we need to see the log generated by yuzu. This guide will walk you through how you can obtain the log file: Getting Log Files - yuzu

Its AMD Radeon 520 also what is the best config
You would suggest for this

Can I run Vulkan on this

It can run yuzu, but expect low performance.
Make sure to use the latest GPU drivers for it: https://www.amd.com/en/support/graphics/radeon-500-series/radeon-500-series/radeon-520

What is the best config. You would recommend for this setup

Recommended settings general applies.